Class Subjects Major of Cognitive and Emotional Neuroscience

Outlines of Majors

Recently, incidence of dementia in longevity societies and problems due to emotional and behavioral abnormalities in juveniles are increasing. The brain is the only organ that develops during the lifetime under the influences of various factors such as many molecules produced from genes, the antenatal environment, and the environment of the external world after birth (social environment). Abnormalities in these material processes in the brain lead to emotional and behavioral abnormalities, while these emotional and behavioral abnormalities affect these material processes and change not only the brain structure but also the physiological functions.
This major aims to develop sophisticated healthcare staff and leading brain scientists who can independently deal with mental problems and emotional/behavioral abnormalities, which are rapidly becoming problematic in developed countries, by overviewing them through interdisciplinary research approaches including specialized fields of basic medicine at the molecular, cellular, and system behavior levels as well as clinical medicine and human social sciences. The goal of this major is to establish science for humanity (“integrated science of the mind”), and the following items are targeted:

  • Neuroscience-based resolution of recognition/emotion/memory
  • Neuroscience in the development of emotional and mental behavioral disorders
  • Neuroscience in the development of higher brain dysfunction and development of preventive care
  • Establishment of molecular biological basis for brain development
  • Promotion of brain-scientific researches by utilizing the combined grounds of medical sciences and pharmaceutical sciences and drug discovery
  • Cross-sectoral analysis of neural information networks

List of Class Subjects

Educational area Responsible teacher Research contents
System Emotional Science Professor
Hisao Nishijo
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Associate Professor
Hiroshi Nishimaru
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  • Neural mechanisms of emotion, learning/memory, and behavioral expression in the limbic system
  • Neural mechanisms of social cognition and non-verbal communication
  • Non-invasive functional brain mapping of human higher brain functions
  • Neural mechanisms of stress and brain development
  • Central control of autonomic nervous functions
  • Neural mechanisms of chemical senses (taste and olfactory sensation)
Molecular Brain Science Professor
Kaoru Inokuchi
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We aim to resolve the molecular mechanism of memory formation in mammals by making full use of molecular biology, biochemistry, cell biology, histochemistry, electrophysiology, and behavioral pharmacology. Specific research contents are indicated below:

  • Research on molecular mechanisms of memory formation
  • Research on synaptic plasticity in the brain
  • Research on destabilization and reconsolidation of fear memory
  • Research on neural circuit mechanisms of memory formation
Molecular Neuroscience Professor
Hisashi Mori
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Associate Professor
TomoyukiYoshida
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  • Analysis of molecular basis of higher brain functions such as cognition, emotion, and sociality with generation of novel genetically modified mouse models.
  • Development of novel imaging methods detecting gene expression in the brain.
  • Analysis of molecular basis of neuro-immnune interactions.
  • Research on molecular mechanisms of central synapse formation.
  • Research on pathogenic mechanisms of neurodevelopmental disorders.
Integrative Neuroscience Professor
Ryoi Tamura
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  • Neural mechanisms of learning and memory in the hippocampal formation
  • Temporal coding in the hippocampal formation
  • Cortico-hippocampal interplay
  • Mechanism for memory consolidation in sleep
  • Functional analyses of eye movements
  • Mechanisms of gustatory information processing in the central nervous system
  • Adult neurogenesis
Molecular Neuropathology Professor
Masakiyo Sasahara
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  • We aim to resolve the functional role of platelet-derived growth factor (PDGF) in various biological phenomena. We establish conditional knockout mouse models of PDGF receptors, and analyze these models and the cultured cells isolated from them. Cell biology and morphology are the major tools of our analyses.
  • Our studies are focusing on the coordination of higher brain function, and on the protection, repair and regenerative mechanism of nervous system. Fibroproliferative diseases and regenerative tissue responses are focused as well.
Neuropsychiatry Professor
Michio Suzuki
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Associate Professor
Tsutomu Takahashi
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  • Pathophysiology of schizophrenia and development of objective diagnostic methods by brain imaging
  • Pharmacotherapy to improve cognitive dysfunction in schizophrenia
  • Animal models of schizophrenia
  • Mechanisms of brain maturation, personality development, and sociality in adolescence
  • Pathophysiology of dementia and development of novel diagnostic methods in the early stage
Neurosurgery Professor
Satoshi Kuroda
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  • Basic and clinical research on pathophysiology and treatment in cerebral ischemia
  • Clinical research on surgical technique and perioperative management in surgical revascularization
  • Basic and clinical research on neuroendovascular surgery
  • Basic and translational research on regenerative medicine in central nervous
  • Basic and clinical research on pathophysiology and surgical therapy of
  • Basic and clinical research on pathophysiology and surgical therapy in pediatric
  • Clinical research on multidisciplinary treatment for brain tumor
  • Basic and translational research on cancer stem cell in central nervous system
  • Clinical research on less invasive surgery by neuroendoscopy
  • Translational research on development of the devices for surgical procedure and functional recovery
Anatomy and Neuroscience Professor
Hiroyuki Ichijo
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  • Animals move toward favorable environments: feeding and mating, and escape from unfavorable stressful environments. These behaviors governed by specific neural circuits are selected through natural selection in evolution. Our purpose is to understand structure and function of neural circuits for the behaviors in evolutionary aspects.
  • Research on neural mechanisms of antero-posterior topography, left-right lateralization, and maturation of habenular nuclei under stress or aversive environments in mice.
  • Research on neural mechanisms of asymmetric behaviors in scale-eating cichlids.
  • Research on neural mechanisms of differential behaviors between courtship and refusal in goby fishes, Rhinogobius flumineus.
  • Research on evolutionary mechanisms of animal innate behaviors in individual-based model simulation.
Behavioral Physiology Professor
Keizo Takao
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  • 記憶・学習、情動、認知などの精神機能の生理的基盤の解明
  • 行動解析による精神・神経疾患モデルマウスの探索と評価
  • モデルマウスを用いた精神・神経疾患の病態解明と治療法の開発
  • 生殖発生工学による新たな遺伝子改変マウスの作製
  • 新しい生殖発生工学技術の開発
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