Class Subjects Major of Biologicl Information Systems

Outlines of Majors

To clarify the mechanisms of biological systems in the “post-genome age,” the need for multilateral observation and understanding of concurrently ongoing phenomena in living organisms has been increasing. In addition, the development of a methodology to obtain, analyze, and understand an enormous amount of information efficiently is required even in future standard medical care system represented by gene diagnosis and personalized medicine. Moreover, in accordance with the rapid development of life science, development is sought of a new biological system science, intellectual information engineering, and medical engineering, which will enable a rapid response to aging welfare societies and health enhancement societies. Under these circumstances, this department is to cultivate leading life scientists who will research and reveal the processes and mechanisms of complicated life phenomena, which keep changing, and unresolved gene information and its expression/regulation mechanisms mainly at the level from molecules and cells to tissues. Furthermore, based on the latest findings on microbiological information-processing mechanisms, leading researchers and advanced engineers who can design and develop devices for body function measurement, medical measurement, and environmental measurement, as well as advanced engineers and pharmacists who can understand and use advanced medical devices and leading-edge information engineering are to be cultivated. We also aim to develop human resources who acquire recent findings and cross-sectoral analysis methods on the brain nerve network as a biological information system in collaboration with departments of cognitive and emotional neuroscience and who contribute to the design and development of next-generation intellectual information engineering, brain-type computers, and human interfaces. In this department, we resolve the biological information system at such micro levels in collaboration with staff in medical (concurrent) departments, pharmacological departments, biological departments, bioengineering departments, and information engineering departments.

List of Class Subjects

教育分野 指導教員 研究内容
Structural Biology Professor
Mineyuki Mizuguchi
We determine protein conformation by NMR to analyze functions and conduct researches on the relation between changes in protein structures and diseases by examination of abnormal structures such as amyloid fibril.
Molecular Genetics Professor
Yoshiaki Tabuchi
  • Mechanical control of cell differentiation.
  • Elucidation of molecular mechanism of cellular stress response.
Consilienceology for Wakan-yaku Associate Professor
Michihisa Tohda
The following studies based on the classical scientific theory systems for Wakan-yaku and Kampo medicine; [Targetted diseases] functional mental diseases (depression, schizophrenia, developmental disability), heart failure; [Academic bases for studies] Jin Gui Yao Lue, the traditional Japanese medicine, the traditional medicine originated in China, physiology, biochemistry and pharmacology; [Strategy and purpose] 1) Diagnosis for functional mental diseases based on the Wakan-yaku response (=Sho), clarification of the molecular mechanisms for diseases, and development of novel Wakan-yaku prescriptions. 2) development of novel Wakan-yaku prescriptions to prevent lethal recurrence of heart failure
Biological Information Engineering Professor
Masaharu Isobe
Based on genetic information, which is a design plan of life, we conduct genetic analysis to approach the cause of onset of diseases such as dementia and cancer, and research on the development of therapeutic methods applying immunological techniques.
Biological Information Engineering Professor
Nobuyuki Kurosawa
We are studying to identify causative genes of adult T cell leukemia by analyzing genetical and epigenetical changes of genes on chromosome 14 in leukemic cells, and have tried to understand the molecular mechanism underlying the leukemogenesis.
We also have been tried to build up a high-throughput system for analyzing gene expression level from small amount of samples, like single cells by by applying genetic engineering technologies.
Bioelectronics Professor
Hiroaki Shinohara
We provide education and conduct researches concerning the design of interfaces that connect biological systems and electronic systems, including synthesis of artificial bio molecules with information transduction function systems, design/development of sensitive and rapid biosensing systems with the use of new measurement devices, and design/development of bioelectronics systems comprising modified biological molecules and cells and electronic devices in combination.
Biosensing Engineering Professor
Masayasu Suzuki
We focus on miniaturization and integration of biosensors. We are developing immunosensors and enzyme sensors for clinical diagnosis, bioscience and environmental science. Especially, the biosensing technology for single cell analysis is our recent major target.
Brain and Nevral System Emgineering Professor
Shigenori Kawahara
By using a relatively simple associative learning task, eyeblink conditioning, we conduct researches on cross-domain interaction in the brain and the hierarchical regulation mechanism from the viewpoint of system theory.
Tissue and organ engineering Professor
Makoto Nakamura
We are aiming at creating and developing some innovative technologies in tissue and organ engineering, specially focussing on Bioprinting and Biofabrication, in which 3D printing technologies are used to construct 3D complicated tissues with multi-cell type. Through these researches, we would like to establish a scientific and engineering methodology to produce engineered tissues and organs using cells and bio-functional materials.
Comparative Neuroendocrinology Professor
Kouhei Matsuda
The aims of my research are to understand the evolutionary background of the neuropeptide-regulated system of feeding and emotional behaviors in lower vertebrates.
Pharmacology Associate Professor
Ichiro Takasaki
Our subject of research is a”pain”, especially chronic pain such as neuropathic pain.
Our aims are to clarify the mechanisms in which the pain becomes and to develop a new drug for the pain.
Medical Design Professor
Toshihide Tabata
We develop medical devices and services including pharmaceutical products, employing techniques including design thinking and biodesign. We search for patients and/or medical providers’ unmet needs, observing their behavior and then create a solution through constructive brain-storming.